Webparallel, a synthetic form of dsRNA, poly(I):poly(C) [poly(I:C)], was transfected as a positive control. As reported (10), dsRNA but not ssRNA induced IFN- expression in Huh-7 cells (Fig. ... (RIG-IC) together with the IFN- promoter luciferase reporter, and we examined them for IFN- promoter activity with and without transfection of WebFinally, long poly I:C required SR-A, whereas short poly I:C required RIG-I and Raftlin. We provide evidence that the length of dsRNA drives distinct innate responses in different cell …
Proposed role of IFIT1, IFIT2, and IFIT3 in the dsRNA-induced...
WebResults A specific formulation of poly-IC, containing poly-lysine and carboxymethylcellulose (PICLC) facilitated the traffic and infiltration of effector CD8 T cells into the tumors that … WebLow molecular weight polyinosine-polycytidylic acid (i.e. poly (I:C)) is a synthetic analog of double-stranded RNA (dsRNA) and is comprised of short strands of inosine poly (I) … e190 takeoff flaps
Protective role for PAR4 in respiratory RNA virus infection
WebMar 4, 2013 · Mast cells contribute to dsRNA-induced augmentation of airway eosinophilia and IL-13 production. In our previous study, an administration of poly IC (10 μg/mouse) during OVA sensitization augmented airway eosinophilia and AHR in OVA-challenged BALB/c mice [].These augmented asthma phenotypes were associated with enhanced production … WebJun 1, 2014 · to poly-IC, suggesting dsRNA signaling plays a role in the. etiology of myasthenia gravis, which is a neurological au-toimmune disease (Cufi and others 2013). … WebPoly (I:C) HMW is a high molecular weight, synthetic analog of double-stranded RNA (dsRNA) and is a potent inducer of IFN. It is cell culture tested to guarantee specific … Polyinosinic-polycytidylic acid (poly(I:C)) is a synthetic analog of double stranded … Poly(I:C) HMW VacciGrade™ is a synthetic analog of double-stranded RNA (dsRNA) … Poly(I:C) HMW, with an average size of 1.5-8 kb, comprises long strands of inosine … Polyinosinic-polycytidylic acid (poly(I:C)) is a synthetic analog of double stranded … Poly(I:C) is structurally similar to dsRNA, present in some viruses, and is therefore … Poly(A:U) is provided lyophilized. 10 mg sterile lyophilized poly(A:U). 10 ml sterile … Murine TLR3 / NF-κB–SEAP reporter HEK293 cells. HEK-Blue™-mTLR3 cells … HEK-Blue™ hTLR3 cells were obtained by co-transfection of the human TLR3 gene … csf tutoring